Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.64 |
| ▸ | FYN | P06241 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | APEX1 | P27695 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | MTOR | P42345 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7107116 | 1.00 | MAPT (0.64) | MAPTBLMKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9422794 | 1.00 | MAPT (0.64) | MAPTBLMKDM4EALDH1A1CYP1A2 | |
| SCHEMBL6348579 | 0.87 | CYP1A2 (0.74) | MAPTBLMKDM4EALDH1A1CYP1A2 | |
| SCHEMBL6718607 | 0.87 | CYP1A2 (0.74) | MAPTBLMKDM4EALDH1A1CYP1A2 | |
| SCHEMBL6348576 | 0.87 | CYP1A2 (0.74) | MAPTBLMKDM4EALDH1A1CYP1A2 | |
| SCHEMBL29346265 | 0.84 | CYP1A2 (0.57) | MAPTBLMKDM4EALDH1A1CYP1A2 | |
| SCHEMBL29346264 | 0.84 | CYP1A2 (0.57) | MAPTBLMKDM4EALDH1A1CYP1A2 | |
| SCHEMBL5539129 | 0.81 | BLM (0.71) | MAPTBLMKDM4EALDH1A1CYP1A2 | |
| SCHEMBL5539133 | 0.81 | BLM (0.71) | MAPTBLMKDM4EALDH1A1CYP1A2 | |
| SCHEMBL29346188 | 0.80 | TDP1 (0.52) | MAPTBLMKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994617-A | Analgesics | JOUVEINAL S.A. (FR) | 1991-02-19 | — | — | US | disclosed |
| EP-0237366-B1 | AMINO ALCOHOLS, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATIONS, IN PARTICULAR FOR THEREPEUTICAL USE | JOUVEINAL S.A. (FR) | 1989-04-26 | — | — | EP | disclosed |
| EP-0237366-A1 | Amino alcohols, process for their preparation and their applications, in particular for therepeutical use | JOUVEINAL S.A. (FR) | 1987-09-16 | — | — | EP | disclosed |