Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 6/20 | 0.31 |
| ▸ | CA2 | P00918 | 6/20 | 0.31 |
| ▸ | CA9 | Q16790 | 6/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3097694 | 0.83 | CA1 (0.41) | TSHRHCAR2HPGDCA1CA2 | |
| SCHEMBL543795 | 0.81 | CA1 (0.43) | TSHRHCAR2HPGDCA1CA2 | |
| SCHEMBL76191 | 0.81 | CA1 (0.43) | TSHRHCAR2HPGDCA1CA2 | |
| SCHEMBL2781039 | 0.81 | CA1 (0.43) | TSHRHCAR2HPGDCA1CA2 | |
| SCHEMBL5144532 | 0.81 | CA1 (0.43) | TSHRHCAR2HPGDCA1CA2 | |
| SCHEMBL2537728 | 0.81 | CA1 (0.43) | TSHRHCAR2HPGDCA1CA2 | |
| SCHEMBL36807 | 0.78 | — | — | |
| SCHEMBL76345 | 0.76 | CYP3A4 (0.42) | TSHRALDH1A1HCAR2HPGDCA1 | |
| SCHEMBL8837209 | 0.75 | CA1 (0.39) | TSHRHCAR2HPGDCA1CA2 | |
| SCHEMBL16341193 | 0.72 | CYP3A4 (0.39) | TSHRALDH1A1HCAR2HPGDCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5000866-A | Antifreeze compositions containing alkane tetracarboxylic acid for use with hard water | FIRST BRANDS CORPORATION (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0217340-B1 | CARBOXY-SUBSTITUTED ORGANOSILICON STABILIZERS FOR A SILICATE-CONTAINING ANTIFREEZE | UNION CARBIDE CORPORATION (US) | 1990-12-12 | — | — | EP | disclosed |
| US-4822901-A | Carboxy-substituted organosilicon stabilizers for a silicate-containing antifreeze | UNION CARBIDE CORPORATION (US) | 1989-04-18 | — | — | US | disclosed |
| US-4772408-A | CORROSION RESISTANCE, GELATION INHIBITION | FIRST BRANDS CORPORATION (US) | 1988-09-20 | — | — | US | disclosed |
| US-4767599-A | Silicate-containing antifreeze with carboxy-substituted organosilicon stabilizer | FIRST BRANDS CORPORATION (US) | 1988-08-30 | — | — | US | disclosed |
| US-4725405-A | Organosiloxane-silicate copolymer antifreeze composition with nitrate corrosion inhibitor | FIRST BRANDS CORPORATION (US) | 1988-02-16 | — | — | US | disclosed |
| US-4701277-A | Silicate-containing antifreeze with carboxy-substituted organosilicon stabilizer | FIRST BRANDS CORPORATION (US) | 1987-10-20 | — | — | US | disclosed |
| US-4684475-A | Organophosphate and silicate containing antifreeze | FIRST BRANDS CORPORATION (US) | 1987-08-04 | — | — | US | disclosed |
| US-4676919-A | Low pH-buffered silicon/silicate antifreeze concentrates | FIRST BRANDS CORPORATION (US) | 1987-06-30 | — | — | US | disclosed |
| US-4664833-A | AUTOMOBILE COOLANTS | UNION CARBIDE CORPORATION (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0217340-A2 | Carboxy-substituted organosilicon stabilizers for a silicate-containing antifreeze | UNION CARBIDE CORPORATION (US) | 1987-04-08 | — | — | EP | disclosed |
| EP-0105803-B1 | ORTHOSILICATE ESTER CONTAINING HEAT TRANSFER FLUIDS | UNION CARBIDE CORPORATION (US) | 1986-06-18 | — | — | EP | disclosed |
| US-4460478-A | GLYCOL, ORGANIC ORTHO-SILICATE, CORROSION RESISTANCE | UNION CARBIDE CORPORATION (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0105803-A1 | Orthosilicate ester containing heat transfer fluids | UNION CARBIDE CORPORATION (US) | 1984-04-18 | — | — | EP | disclosed |
| EP-0097583-A2 | Aluminum corrosion inhibitor composition comprising a graft copolymer and a silicate | UNION CARBIDE CORPORATION (US) | 1984-01-04 | — | — | EP | disclosed |
| US-4404114-A | AQUEOUS OR ALCOHOLIC SOLUTION OF AN UNSATURATED ACID-POLYETHER GRAFT POLYMER AND A SILICATE; SOLAR CELLS; INTERNAL COMBUSTION ENGINES | UNION CARBIDE CORPORATION (US) | 1983-09-13 | — | — | US | disclosed |