Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Butoxyethanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethanolamine SCHEMBL9559928 | 0.94 | TSHR (0.65) | TSHRMEN1KMT2ATHRBHTT | |
| Butoxyethanol SCHEMBL10983791 | 0.89 | TSHR (0.74) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL11454239 | 0.89 | TSHR (0.60) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL11464379 | 0.89 | TSHR (0.60) | TSHRMEN1KMT2ATHRBHTT | |
| Butoxyethanol SCHEMBL1430848 | 0.87 | — | — | |
| Diethanolamine SCHEMBL28842690 | 0.85 | MEN1 (0.65) | TSHRMEN1KMT2ATHRBHTT | |
| Water SCHEMBL7866492 | 0.84 | TSHR (0.90) | TSHRMEN1KMT2ATHRBHTT | |
| Butoxyethanol SCHEMBL28192530 | 0.84 | TSHR (0.90) | TSHRMEN1KMT2ATHRBHTT | |
| Water SCHEMBL3115902 | 0.84 | TSHR (0.90) | TSHRMEN1KMT2ATHRBHTT | |
| Butoxyethanol SCHEMBL15712 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034279-A | Electrophoretically depositable coating composition of a curable resin, a reaction betueen an epoxy and a crosslinking agent | MINNESOTA MINING & MANUFACTURING COMPANY (US) | 1991-07-23 | — | — | US | disclosed |
| US-4913968-A | IONIC OR NONIONIC CURED POLYEPOXIDES; BULKY-STRUCTURED CROSSLINKER | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-04-03 | — | — | US | disclosed |
| US-4904360-A | Water-compatible coating composition | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-02-27 | — | — | US | disclosed |
| US-4822464-A | Water-compatible coating resin | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-04-18 | — | — | US | disclosed |
| EP-0260009-A2 | Water-compatible coating composition | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-03-16 | — | — | EP | disclosed |
| EP-0260010-A2 | Water-compatible coating resin | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-03-16 | — | — | EP | disclosed |