Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | GLA | P06280 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 6/20 | 0.53 |
| ▸ | MAOA | P21397 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360138 | 0.88 | MAPT (0.71) | MAPTKDM4EGLAMAPK1NPC1 | |
| SCHEMBL9778219 | 0.86 | MAOB (0.42) | MAPTKDM4EGLAMAPK1NPC1 | |
| SCHEMBL9778371 | 0.85 | MAOB (0.48) | MAPTKDM4EGLAMAPK1NPC1 | |
| SCHEMBL9778252 | 0.77 | MAOB (0.48) | MAPTKDM4EGLAMAPK1NPC1 | |
| SCHEMBL9778249 | 0.77 | MAPKAPK2 (0.48) | MAPTKDM4EGLAMAPK1NPC1 | |
| SCHEMBL157594 | 0.73 | MAPT (1.00) | MAPTKDM4EGLAMAPK1NPC1 | |
| SCHEMBL2985023 | 0.72 | MAOB (1.00) | MAPTKDM4EMAOBMAOAALDH1A1 | |
| SCHEMBL9359536 | 0.69 | MAPT (0.77) | MAPTKDM4EGLAMAPK1NPC1 | |
| SCHEMBL4626134 | 0.69 | MAPT (0.77) | MAPTKDM4EGLAMAPK1NPC1 | |
| SCHEMBL11211211 | 0.69 | KDM4E (0.77) | MAPTKDM4EGLAMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992203-A | Element comprising pyrazoline compound aligned for net non-centrosymmetry | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-12 | — | — | US | disclosed |