SCHEMBL977894

SCHEMBL977894

C=C(C)C(=O)OCC(C)CC[Si](OC)(OC)OC

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.53
ALDH1A1 P00352 2/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL975918 0.87 TSHR (0.53) TSHRALDH1A1THRB
SCHEMBL615161 0.83 TSHR (0.56) TSHRALDH1A1THRB
SCHEMBL27797460 0.83 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL4526188 0.82 TSHR (0.69) TSHRALDH1A1THRB
SCHEMBL3319370 0.78 TSHR (0.75) TSHRALDH1A1THRB
SCHEMBL23493920 0.78 TSHR (0.68) TSHRALDH1A1THRB
SCHEMBL2156739 0.78 TSHR (0.62) TSHRALDH1A1THRB
SCHEMBL28387209 0.78 TSHR (0.62) TSHRALDH1A1THRB
SCHEMBL1902015 0.78 TSHR (0.62) TSHRALDH1A1THRB
SCHEMBL2407963 0.78 TSHR (0.62) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101405315-B Moisture-curing compositions containing silane-functional polymers with good adhesive properties SIKA TECHNOLOGY AG 2011-04-13 CN disclosed
US-7867619-B2 Moisture-curing compositions containing silane-functional polymers with good adhesive properties SIKA TECHNOLOGY AG (CH) 2011-01-11 US disclosed
EP-1981924-B1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS WITH GOOD ADHESIVE PROPERTIES SIKA TECHNOLOGY AG (CH) 2010-03-31 EP disclosed
US-20090214879-A1 Moisture-Curing Compositions Containing Silane-Functional Polymers With Good Adhesive Properties SIKA TECHNOLOGY AG (CH) 2009-08-27 US disclosed
CN-101405315-A Moisture-curing compositions containing silane-functional polymers with good adhesive properties SIKA TECHNOLOGY AG (CH) 2009-04-08 CN disclosed
EP-1981924-A1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS WITH GOOD ADHESIVE PROPERTIES Sika Technology AG (CH) 2008-10-22 EP disclosed
WO-2007085620-A1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS WITH GOOD ADHESIVE PROPERTIES SIKA TECHNOLOGY AG (CH) 2007-08-02 WO disclosed