Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 10/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779113 | 0.90 | SLC2A1 (0.48) | SLC2A1HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL9779167 | 0.88 | SLC2A1 (0.41) | SLC2A1HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL9778957 | 0.85 | SLC2A1 (0.41) | SLC2A1KDM4ELMNAGAA | |
| SCHEMBL9779025 | 0.83 | SLC2A1 (0.36) | SLC2A1HPGDALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL9535783 | 0.82 | SLC2A1 (0.38) | SLC2A1HPGDALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL9779107 | 0.81 | SLC2A1 (0.43) | SLC2A1HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL9536974 | 0.81 | SLC2A1 (0.48) | SLC2A1HPGDALDH1A1MAPTKDM4E | |
| SCHEMBL9537874 | 0.81 | SLC2A1 (0.41) | SLC2A1ALDH1A1MAPT | |
| SCHEMBL10630223 | 0.81 | SLC2A1 (0.48) | SLC2A1HPGDALDH1A1KDM4E | |
| SCHEMBL9779041 | 0.79 | SLC2A1 (0.46) | SLC2A1CYP2C19CYP3A4LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999369-A | Antitumor agents | BURROUGHS WELLCOME CO. (US) | 1991-03-12 | — | — | US | disclosed |
| US-4952597-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1990-08-28 | — | — | US | disclosed |
| US-4918101-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1990-04-17 | — | — | US | disclosed |
| US-4910218-A | With a hydroxy containing secondary amine group | BURROUGHS WELLCOME CO. (US) | 1990-03-20 | — | — | US | disclosed |
| US-4873258-A | Benzo[c] carbazole propanediol containing anti tumor compositions and use | BURROUGHS WELLCOME CO. (US) | 1989-10-10 | — | — | US | disclosed |