SCHEMBL9779666

SCHEMBL9779666

CCCCC[C@H]1CC[C@H](c2ccc(-c3cc(N)ccc3-c3ccccc3F)cc2)CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.36
CYP3A4 P08684 2/20 0.35
MAPT P10636 2/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
MEN1 O00255 1/20 0.34
MAPK1 P28482 1/20 0.34
KMT2A Q03164 1/20 0.34
SPHK1 Q9NYA1 2/20 0.34
APP P05067 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
GAA P10253 1/20 0.32
TLR8 Q9NR97 1/20 0.32
ESR2 Q92731 1/20 0.32
DGAT1 O75907 1/20 0.31
SOAT1 P35610 1/20 0.31
GRM2 Q14416 1/20 0.31
ALOX5AP P20292 2/20 0.31
FEN1 P39748 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9561423 0.87 CYP2C9 (0.40) CYP2C9CYP3A4MAPTALDH1A1LMNA
SCHEMBL9501064 0.87 CYP2C9 (0.40) CYP2C9CYP3A4MAPTALDH1A1LMNA
SCHEMBL9779634 0.85 KDM1A (0.37) CYP2C9CYP3A4CNR1CNR2
SCHEMBL9779710 0.84 CYP2C9 (0.42) CYP2C9CYP3A4MAPTALDH1A1LMNA
SCHEMBL9779457 0.84 RARB (0.45) CYP2C9CYP3A4MAPTALDH1A1LMNA
SCHEMBL9779705 0.83 CYP2C9 (0.42) CYP2C9CYP3A4MAPTALDH1A1LMNA
SCHEMBL9779697 0.83 CYP2C9 (0.42) CYP2C9CYP3A4MAPTALDH1A1LMNA
SCHEMBL9779469 0.82 KDM1A (0.37) CYP2C9CYP3A4
SCHEMBL30475372 0.81 CYP2C9 (0.40) CYP2C9CYP3A4MAPTALDH1A1LMNA
SCHEMBL7663407 0.81 GAA (0.42) CYP2C9CYP3A4MAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5061400-A WIDE TEMPERATURE RANGE, HIGH RESPONSE SPEED, LOW DRIVING VOLTAGE SEIKO EPSON CORPORATION (JP) 1991-10-29 US disclosed