Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 5/20 | 0.55 |
| ▸ | CA2 | P00918 | 5/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710 | 0.97 | GAA (0.64) | GAARAB9AMAPTTDP1NPC1 | |
| SCHEMBL28983971 | 0.95 | GAA (0.61) | GAARAB9AMAPTTDP1NPC1 | |
| SCHEMBL29896240 | 0.95 | GAA (0.61) | GAARAB9AMAPTTDP1NPC1 | |
| Phosphine SCHEMBL8863649 | 0.95 | GAA (0.61) | GAARAB9AMAPTTDP1NPC1 | |
| Bromide SCHEMBL20984524 | 0.95 | GAA (0.61) | GAARAB9AMAPTTDP1NPC1 | |
| Hydrochloric Acid SCHEMBL129453 | 0.95 | GAA (0.61) | GAARAB9AMAPTTDP1NPC1 | |
| SCHEMBL8863654 | 0.95 | GAA (0.61) | GAARAB9AMAPTTDP1NPC1 | |
| Hydrochloric Acid SCHEMBL11741196 | 0.95 | GAA (0.61) | GAARAB9AMAPTTDP1NPC1 | |
| Water SCHEMBL721160 | 0.95 | GAA (0.61) | GAARAB9AMAPTTDP1NPC1 | |
| Hydrochloric Acid SCHEMBL9188152 | 0.93 | GAA (0.58) | GAARAB9AMAPTTDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996223-A | Substituted 1,2,3,4-tetrahydrocarbazoles as analgesics; side effect reduction | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 1991-02-26 | — | — | US | disclosed |