Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL977994

C1=Cc2cccc3cccc(c23)C1.N.N

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
CYP3A4 P08684 2/20 0.41
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
ALDH1A1 P00352 4/20 0.35
HSD17B10 Q99714 4/20 0.35
HPGD P15428 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP1A1 P04798 1/20 0.35
CYP1B1 Q16678 1/20 0.35
KDM4E B2RXH2 2/20 0.34
CYP2C19 P33261 2/20 0.33
CYP2D6 P10635 1/20 0.33
TYMS P04818 1/20 0.32
LMNA P02545 1/20 0.32
PARP1 P09874 1/20 0.32
MAPK1 P28482 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL10534318 1.00 TSHR (0.41) TSHRCYP3A4CA1CA2ALDH1A1
Ammonia Solution, Strong SCHEMBL2143516 1.00 TSHR (0.41) TSHRCYP3A4CA1CA2ALDH1A1
Ammonia Solution, Strong SCHEMBL21830397 1.00 TSHR (0.41) TSHRCYP3A4CA1CA2ALDH1A1
Fluoride SCHEMBL27714588 0.98 CYP3A4 (0.40) TSHRCYP3A4CA1CA2ALDH1A1
Ammonia Solution, Strong SCHEMBL7262979 0.98 CYP3A4 (0.40) TSHRCYP3A4CA1CA2ALDH1A1
Fluoride SCHEMBL27714590 0.98 CYP3A4 (0.40) TSHRCYP3A4CA1CA2ALDH1A1
Ammonia Solution, Strong SCHEMBL28887351 0.98 CYP3A4 (0.40) TSHRCYP3A4CA1CA2ALDH1A1
Methane SCHEMBL17330285 0.98 CYP3A4 (0.40) TSHRCYP3A4CA1CA2ALDH1A1
SCHEMBL7432807 0.98 TSHR (0.43) TSHRCYP3A4CA1CA2ALDH1A1
SCHEMBL17685497 0.98 TSHR (0.43) TSHRCYP3A4CA1CA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11834697-B2 Electrochemical recognition and quantification of cytochrome c oxidase expression in bacteria OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2023-12-05 US disclosed
EP-3682019-A1 ELECTROCHEMICAL RECOGNITION AND QUANTIFICATION OF CYTOCHROME C OXIDASE EXPRESSION IN BACTERIA Oxford University Innovation Limited (GB) 2020-07-22 EP disclosed
US-20200199644-A1 ELECTROCHEMICAL RECOGNITION AND QUANTIFICATION OF CYTOCHROME C OXIDASE EXPRESSION IN BACTERIA OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2020-06-25 US disclosed
WO-2019053467-A1 ELECTROCHEMICAL RECOGNITION AND QUANTIFICATION OF CYTOCHROME C OXIDASE EXPRESSION IN BACTERIA OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2019-03-21 WO disclosed
EP-3383834-A1 ADDITIVES FOR MITIGATING FOULING DURING THE OXIDATION OF ALKENES Baker Hughes, a GE company, LLC (US) 2018-10-10 EP disclosed
WO-2017096210-A1 ADDITIVES FOR MITIGATING FOULING DURING THE OXIDATION OF ALKENES BAKER HUGHES INCORPORATED (US) 2017-06-08 WO disclosed
US-8440830-B2 Tetrahydro-fused pyridines as histone deacetylase inhibitors 4SC AG (DE) 2013-05-14 US disclosed
US-20110021494-A1 NOVEL TETRAHYDRO-FUSED PYRIDINES AS HISTONE DEACETYLASE INHIBITORS 4SC AG (DE) 2011-01-27 US disclosed
US-4294749-A Process for the coloration of thermoplastic polymers and polycondensates in the mass with water-insoluble disazo-methine compounds HOECHST AKTIENGESELLSCHAFT (DE) 1981-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110021494-A1 NOVEL TETRAHYDRO-FUSED PYRIDINES AS HISTONE DEACETYLASE INHIBITORS HDAC1, HDAC11, HDAC3 TSHR 4060/4885CYP3A4 1362/4885CA1 1993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.