Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | BCR | P11274 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3021858 | 0.78 | EPHX2 (0.57) | EPHX2POLBMAPTKMT2AMEN1 | |
| SCHEMBL5389140 | 0.78 | POLB (0.52) | EPHX2POLBMAPTKMT2AMEN1 | |
| SCHEMBL6289309 | 0.78 | MAPT (0.55) | EPHX2POLBMAPTKMT2AMEN1 | |
| SCHEMBL13813682 | 0.78 | MAPT (0.51) | EPHX2POLBMAPTKMT2AMEN1 | |
| SCHEMBL28519915 | 0.77 | EPHX2 (0.65) | EPHX2POLBMAPTKMT2AMEN1 | |
| SCHEMBL12696684 | 0.77 | EPHX2 (0.51) | EPHX2POLBMAPTKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7471077 | 0.77 | POLB (0.66) | EPHX2POLBMAPTKMT2AMEN1 | |
| SCHEMBL1797885 | 0.77 | POLB (0.66) | EPHX2POLBMAPTKMT2AMEN1 | |
| SCHEMBL5723863 | 0.77 | EPHX1 (0.50) | EPHX2TRPV1 | |
| SCHEMBL169453 | 0.76 | EPHX2 (0.73) | EPHX2MAPTKMT2ARAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026717-A | Glutamate inhibitors | RHONE-POULENC SANTE (FR) | 1991-06-25 | — | — | US | disclosed |
| US-4980356-A | ANTICONVULSANTS; ANTISPASMODIC AGENTS; MUSCULAR AND NERVOUS SYSTEMS DISORDERS | RHONE-POULENC SANTE (FR) | 1990-12-25 | — | — | US | disclosed |