⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9431966 | 0.78 | — | — | |
| SCHEMBL28639832 | 0.75 | TSHR (0.47) | — | |
| SCHEMBL9431512 | 0.75 | — | — | |
| SCHEMBL9431315 | 0.75 | — | — | |
| SCHEMBL9431604 | 0.75 | — | — | |
| SCHEMBL11205067 | 0.75 | — | — | |
| SCHEMBL9431864 | 0.75 | — | — | |
| SCHEMBL10846670 | 0.75 | — | — | |
| SCHEMBL9481025 | 0.71 | — | — | |
| SCHEMBL9418107 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109369618-B | Method for preparing 2-chloro-5- ((2- (nitromethylene) imidazoline-1-yl) methyl) pyridine in one pot | 上海生农生化制品股份有限公司 | 2021-05-11 | — | — | CN | claimed |
| CN-107382736-B | The synthetic method of the chloro- 2- nitroethylene of 1,1- bis- and Nitenpyram | 江苏克胜集团股份有限公司 | 2019-09-03 | — | — | CN | claimed |
| CN-109369618-A | Cook different foods in one pot and prepare the chloro- 5-((2-(Nitromethylene of 2-) imidazoline -1- base) methyl) and pyridine method | 上海生农生化制品股份有限公司 | 2019-02-22 | — | — | CN | claimed |
| CN-107474022-A | Thiazolyl anabasine compound and its preparation method and application | 连云港立本作物科技有限公司 | 2017-12-15 | — | — | CN | claimed |
| CN-107382736-A | The synthetic method of the nitroethylene of 1,1 dichloro 2 and Nitenpyram | 江苏克胜集团股份有限公司 | 2017-11-24 | — | — | CN | claimed |
| CN-105330593-A | Improved preparation method of nitenpyram | SHANGHAI JINJING CHEMICAL CO LTD | 2016-02-17 | — | — | CN | claimed |
| CN-104402806-A | Nitenpyram preparation method | ANHUI JIXI COUNTY HUIHUANG CHEMICAL CO LTD | 2015-03-11 | — | — | CN | claimed |
| EP-0381130-B1 | Production of alpha-unsaturated amines | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-10-04 | — | — | EP | claimed |
| US-5364989-A | Reaction of vinylidene chloride with nitric acid and hydrogen chloride | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-11-15 | — | — | US | claimed |
| US-4968808-A | MULTISTEP IN ONE POT | HEUMANN PHARMA GMBH & CO. (DE) | 1990-11-06 | — | — | US | claimed |
| EP-0381130-A2 | Production of alpha-unsaturated amines | Takeda Chemical Industries, Ltd. (JP) | 1990-08-08 | — | — | EP | claimed |
| EP-0285681-A1 | Process for the preparation of nitroethylene derivatives | HEUMANN PHARMA GMBH & CO (DE) | 1988-10-12 | — | — | EP | claimed |
| US-4625025-A | Process for producing a 2H-1,3-thiazolidine, 2H-tetrahydro-1,3-thiazine, or 2H-hexahydro-1,3-thiazepine derivative substituted at the 2 position by a nitromethylene group derivative | UBE INDUSTRIES, LTD. (JP) | 1986-11-25 | — | — | US | claimed |
| EP-0135803-A2 | Process for producing heterocyclic compounds having nitromethylene group as the side chain group | UBE INDUSTRIES, LTD. (JP) | 1985-04-03 | — | — | EP | claimed |
| CN-118598752-A | Synthesis method of 1, 1-dichloro-2-nitroethylene | 上海生农生化制品股份有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-109369618-B | Method for preparing 2-chloro-5- ((2- (nitromethylene) imidazoline-1-yl) methyl) pyridine in one pot | 上海生农生化制品股份有限公司 | 2021-05-11 | — | — | CN | disclosed |
| CN-109369618-B | Method for preparing 2-chloro-5- ((2- (nitromethylene) imidazoline-1-yl) methyl) pyridine in one pot | 上海生农生化制品股份有限公司 | 2021-05-11 | — | — | CN | disclosed |
| US-3978228-A | METHOD FOR KILLING NOXIOUS FUNGI IN PLANTS USING DIHALO SULFONATES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) | 1976-08-31 | — | — | US | disclosed |
| US-3966789-A | FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-06-29 | — | — | US | disclosed |
| US-3962223-A | BACTERICIDES | ROUSSEL-UCLAF (FR) | 1976-06-08 | — | — | US | disclosed |