Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 7/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 7/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 3/20 | 0.32 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.32 |
| ▸ | CBFB | Q13951 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780277 | 0.84 | KCNQ3 (0.36) | KCNQ3KCNQ2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9780285 | 0.83 | NPC1 (0.38) | KCNQ3KCNQ2MEN1KMT2AALDH1A1 | |
| SCHEMBL9757641 | 0.80 | SMN1; SMN2 (0.41) | KCNQ3KCNQ2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8650194 | 0.80 | SMN1; SMN2 (0.41) | KCNQ3KCNQ2ALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL9757456 | 0.79 | SMN1; SMN2 (0.40) | KCNQ3KCNQ2ALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL9780264 | 0.79 | SMN1; SMN2 (0.38) | KCNQ3KCNQ2ALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL9757393 | 0.79 | SMN1; SMN2 (0.40) | KCNQ3KCNQ2ALDH1A1SMN1; SMN2MAPT | |
| Bromide SCHEMBL9757460 | 0.79 | SMN1; SMN2 (0.41) | KCNQ3KCNQ2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9780333 | 0.79 | KCNQ3 (0.41) | KCNQ3KCNQ2ALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL9422823 | 0.78 | KCNQ3 (0.38) | KCNQ3KCNQ2ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026717-A | Glutamate inhibitors | RHONE-POULENC SANTE (FR) | 1991-06-25 | — | — | US | disclosed |
| US-4980356-A | ANTICONVULSANTS; ANTISPASMODIC AGENTS; MUSCULAR AND NERVOUS SYSTEMS DISORDERS | RHONE-POULENC SANTE (FR) | 1990-12-25 | — | — | US | disclosed |