SCHEMBL978174

SCHEMBL978174

C=C(C)C(=O)OCCCCC[SiH](OC)OC

nearest known ligand 0.61

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.61
POLB P06746 1/20 0.50
APEX1 P27695 1/20 0.50
HTT P42858 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
THRB P10828 1/20 0.44
ALDH1A1 P00352 4/20 0.38
CYP3A4 P08684 1/20 0.33
NAAA Q02083 1/20 0.32
RAD52 P43351 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16207723 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL16207843 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL6381554 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL16207815 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL35127 0.98 TSHR (0.58) TSHRPOLBAPEX1HTTTDP1
SCHEMBL28228114 0.97 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
SCHEMBL136943 0.93 TSHR (0.55) TSHRPOLBAPEX1HTTTDP1
SCHEMBL10991089 0.88 TSHR (0.47) TSHRPOLBAPEX1HTTTDP1
SCHEMBL19988264 0.87 TSHR (0.46) TSHRPOLBAPEX1HTTTDP1
SCHEMBL5575634 0.87 TSHR (0.46) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3310792-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-07-21 EP claimed
EP-3310792-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-07-21 EP disclosed
EP-3310793-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-06-09 EP disclosed
EP-3235845-B1 PHOTOCURABLE AND THERMOSETTING RESIN COMPOSITION, CURED PRODUCT AND LAMINATE KANEKA CORP (JP) 2020-07-15 EP disclosed
US-10563088-B2 Photocurable and thermosetting resin composition, cured product, and laminate KANEKA CORPORATION (JP) 2020-02-18 US disclosed
US-10273254-B2 Process for preparing an acryloyloxysilane DOW CORNING CORPORATION (US) 2019-04-30 US disclosed
US-10246473-B2 Process for preparing an acryloyloxysilane DOW CORNING CORPORATION (US) 2019-04-02 US disclosed
EP-2785726-B1 ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF; AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS DOW SILICONES CORP (US) 2018-08-01 EP disclosed
US-20180155371-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORPORATION 2018-06-07 US disclosed
US-20180134734-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORPORATION 2018-05-17 US disclosed
EP-2762482-A1 Process for purifying an acryloyloxysilane Dow Corning Corporation (US) 2014-08-06 EP disclosed
EP-2621936-A2 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE Dow Corning Corporation (US) 2013-08-07 EP disclosed
US-20130184482-A1 Process For Preparing An Acryloyloxysilane DOW CORNING CORPORATION (US) 2013-07-18 US disclosed
WO-2013081820-A2 ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF;AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS DOW CORNING CORPORATION (US) 2013-06-06 WO disclosed
WO-2012050761-A2 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW CORNING CORPORATION (US) 2012-04-19 WO disclosed
US-7867619-B2 Moisture-curing compositions containing silane-functional polymers with good adhesive properties SIKA TECHNOLOGY AG (CH) 2011-01-11 US disclosed
US-20090214879-A1 Moisture-Curing Compositions Containing Silane-Functional Polymers With Good Adhesive Properties SIKA TECHNOLOGY AG (CH) 2009-08-27 US disclosed
EP-1234830-B1 Method of preparing an organosilicon compound containing a methacryloxy functional group DOW CORNING TORAY SILICONE (JP) 2005-01-19 EP disclosed
EP-1234830-A2 Method of preparing an organosilicon compound containing a methacryloxy functional group Dow Corning Toray Silicone Co., Ltd. (JP) 2002-08-28 EP disclosed
US-20020115878-A1 METHOD OF PREPARING AN ORGANOSILICON COMPOUND CONTAINING A METHACRYLOXY FUNCTIONAL GROUP DOW TORAY CO., LTD. (JP) 2002-08-22 US disclosed