⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3671670 | 0.79 | — | — | |
| SCHEMBL17868765 | 0.77 | — | — | |
| SCHEMBL4679143 | 0.75 | — | — | |
| SCHEMBL12488481 | 0.71 | — | — | |
| SCHEMBL19175544 | 0.70 | — | — | |
| SCHEMBL7995731 | 0.70 | — | — | |
| SCHEMBL6833847 | 0.70 | — | — | |
| SCHEMBL434342 | 0.70 | — | — | |
| SCHEMBL1394069 | 0.70 | — | — | |
| SCHEMBL7455348 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992544-A | Intermediates for b-lactam antibiotics and b-lactamase inhibitor | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0089216-A2 | Cephalosporin compounds | GLAXO GROUP LIMITED (GB) | 1983-09-21 | — | — | EP | disclosed |
| US-4351766-A | Production of penicillins | BRISTOL-MYERS COMPANY (US) | 1982-09-28 | — | — | US | disclosed |
| US-4316016-A | TRIMETHYLSILYL DERIVATIVES | BRISTOL-MYERS COMPANY (US) | 1982-02-16 | — | — | US | disclosed |
| US-4316017-A | TRIMETHYLSILYL DERIVATIVES | BRISTOL-MYERS COMPANY (US) | 1982-02-16 | — | — | US | disclosed |
| US-4310458-A | PRODUCTION OF AMOXYCILLIN AND AMPICILLIN | BRISTOL-MYERS COMPANY (US) | 1982-01-12 | — | — | US | disclosed |
| US-4297489-A | CEPHALOSPORINS | BRISTOL-MYERS COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
| US-4284766-A | Process for the preparation of cephalosporin compounds | GLAXO GROUP LIMITED (GB) | 1981-08-18 | — | — | US | disclosed |
| US-4284767-A | Process for preparing 3-carbamoyloxymethyl cephalosporins | GLAXO GROUP LIMITED (GB) | 1981-08-18 | — | — | US | disclosed |
| US-4278600-A | CARBONATION, ACID ACCEPTORS, SILATION | BRISTOL-MYERS COMPANY (US) | 1981-07-14 | — | — | US | disclosed |
| US-4068078-A | ANTIBIOTICS | BRISTOL-MYERS CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4066831-A | ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1978-01-03 | — | — | US | disclosed |
| US-4066832-A | ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1978-01-03 | — | — | US | disclosed |
| US-4065623-A | O-2-Isocephem-4-carboxylic acid derivatives as antibacterial agents | BRISTOL-MYERS COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4065622-A | O-2-Isocephem-4-carboxylic acid derivatives as antibacterial agents | BRISTOL-MYERS COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4014872-A | ANTIBIOTICS | GLAXO LABORATORIES LIMITED (EN) | 1977-03-29 | — | — | US | disclosed |
| US-4013648-A | BETA-LACTAM ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
| US-4012383-A | BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1977-03-15 | — | — | US | disclosed |
| US-4011216-A | Δ2,3-0-2-Isocephem-4-carboxylic acid and derivatives thereof as antibacterial agents | BRISTOL-MYERS COMPANY (US) | 1977-03-08 | — | — | US | disclosed |
| US-3960843-A | Process for the preparation of esters of N-blocked penicillin acids which comprises reacting the acid or a salt thereof with a primary amine and a nitrosating agent | GLAXO LABORATORIES LIMITED (EN) | 1976-06-01 | — | — | US | disclosed |