Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783689 | 0.78 | CYP19A1 (0.34) | CYP1A2 | |
| SCHEMBL9783078 | 0.72 | CYP1A2 (0.37) | RAF1CYP1A2CDK1CYP2C9CCNB1 | |
| SCHEMBL9783520 | 0.67 | CYP19A1 (0.42) | RAF1CYP1A2CDK1CYP2C9CCNB1 | |
| SCHEMBL9783086 | 0.66 | CYP1A2 (0.37) | RAF1CYP1A2CDK1CYP2C9CCNB1 | |
| SCHEMBL9783066 | 0.66 | TAAR1 (0.47) | — | |
| SCHEMBL9783769 | 0.60 | PCSK9 (0.40) | CYP1A2 | |
| SCHEMBL24866514 | 0.59 | HPGD (0.41) | RAF1CYP1A2CDK1CYP2C9CCNB1 | |
| SCHEMBL14415465 | 0.59 | HTR1B (0.41) | — | |
| SCHEMBL9783330 | 0.58 | PCSK9 (0.41) | — | |
| SCHEMBL12244444 | 0.57 | HPGD (0.36) | RAF1CYP1A2CDK1CYP2C9CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |