Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783770 | 0.88 | TAAR1 (0.45) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL9783680 | 0.86 | TAAR1 (0.38) | TAAR1HTR1A | |
| SCHEMBL9783645 | 0.82 | TAAR1 (0.33) | TAAR1HTR1A | |
| SCHEMBL9784001 | 0.81 | — | — | |
| SCHEMBL9783026 | 0.80 | TAAR1 (0.37) | TAAR1HTR1A | |
| SCHEMBL9783206 | 0.76 | TAAR1 (0.31) | TAAR1HTR1A | |
| SCHEMBL9784070 | 0.75 | TAAR1 (0.42) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL9783511 | 0.74 | TAAR1 (0.44) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL9783968 | 0.74 | TAAR1 (0.41) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL9783777 | 0.73 | TAAR1 (0.45) | TAAR1HTR1AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |