Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 17/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9996065 | 0.85 | CYP17A1 (0.78) | CYP17A1CYP19A1 | |
| SCHEMBL9784383 | 0.85 | CYP17A1 (0.58) | CYP17A1CYP19A1 | |
| SCHEMBL9784363 | 0.84 | CYP17A1 (0.67) | CYP17A1CYP19A1 | |
| SCHEMBL9784394 | 0.83 | CYP17A1 (0.67) | CYP17A1CYP19A1 | |
| SCHEMBL2348613 | 0.83 | CYP17A1 (0.67) | CYP17A1CYP19A1 | |
| SCHEMBL11706076 | 0.81 | CYP17A1 (0.67) | CYP17A1CYP19A1 | |
| SCHEMBL9791445 | 0.81 | CYP17A1 (0.71) | CYP17A1 | |
| SCHEMBL9784415 | 0.80 | CYP17A1 (0.70) | CYP17A1CYP19A1 | |
| SCHEMBL2352103 | 0.80 | CYP17A1 (0.62) | CYP17A1CYP19A1 | |
| SCHEMBL4578052 | 0.80 | CYP17A1 (0.83) | CYP17A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340153-A1 | N-substituted imidazoles, process for their preparation and their use in medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-11-02 | — | — | EP | claimed |
| US-5045558-A | Aromatase inhibitors, prevention of estrogen biosynthesis, treatment of breast cancer | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |
| EP-0340153-A1 | N-substituted imidazoles, process for their preparation and their use in medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-11-02 | — | — | EP | disclosed |