Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.82 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8269685 | 0.98 | USP2 (0.85) | USP2POLBMAPTTSHRHPGD | |
| SCHEMBL8269659 | 0.88 | USP2 (0.76) | USP2POLBMAPTTSHRHPGD | |
| SCHEMBL13438260 | 0.88 | USP2 (0.93) | USP2POLBMAPTTSHRHPGD | |
| SCHEMBL17009233 | 0.87 | USP2 (0.85) | USP2POLBMAPTTSHRHPGD | |
| SCHEMBL7694996 | 0.87 | USP2 (0.85) | USP2POLBMAPTTSHRHPGD | |
| SCHEMBL17009271 | 0.85 | USP2 (0.88) | USP2POLBMAPTTSHRHPGD | |
| SCHEMBL28179817 | 0.83 | USP2 (0.84) | USP2POLBMAPTTSHRHPGD | |
| SCHEMBL17205973 | 0.83 | USP2 (0.84) | USP2POLBMAPTTSHRHPGD | |
| SCHEMBL25283374 | 0.82 | USP2 (0.82) | USP2POLBMAPTTSHRHPGD | |
| SCHEMBL17009332 | 0.82 | USP2 (0.82) | USP2POLBMAPTTSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003106-A | Antiatherosclerotic ureas and thioureas | AMERICAN CYANAMID COMPANY (US) | 1991-03-26 | — | — | US | disclosed |