Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.30 |
| ▸ | HTR3B | O95264 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.30 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9786417 | 1.00 | BCHE (0.33) | BCHECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9731526 | 1.00 | BCHE (0.33) | BCHECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9731529 | 1.00 | BCHE (0.33) | BCHECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9786420 | 1.00 | BCHE (0.33) | BCHECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9786407 | 1.00 | BCHE (0.33) | BCHECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9732299 | 0.94 | BCHE (0.32) | BCHECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9732305 | 0.94 | BCHE (0.32) | BCHECHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL16077036 | 0.93 | BCHE (0.31) | BCHE | |
| SCHEMBL9731561 | 0.84 | ABCB1 (0.31) | — | |
| SCHEMBL9731567 | 0.84 | ABCB1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013758-A | Novel carbacyclins, processes for their preparation and their use as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-05-07 | — | — | US | disclosed |