Chrysene

Chrysene

SCHEMBL9786466

c1ccc2c(c1)ccc1c3ccccc3ccc21.c1ccc2c(c1)ccc1ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 4/20 1.00
ALDH1A1 P00352 4/20 0.86
HSD17B10 Q99714 4/20 0.86
TSHR P16473 3/20 0.86
TDP1 Q9NUW8 2/20 0.86
CYP2A6 P11509 2/20 0.86
HIF1A Q16665 3/20 0.67
CYP1B1 Q16678 1/20 0.67
PAX8 Q06710 1/20 0.65
CYP1A2 P05177 4/20 0.58
HPGD P15428 3/20 0.58
THRB P10828 1/20 0.58
MAPK1 P28482 3/20 0.56
LMNA P02545 2/20 0.56
CYP3A4 P08684 2/20 0.56
MAPT P10636 1/20 0.56
APEX1 P27695 1/20 0.56
PMP22 Q01453 1/20 0.56
MEN1 O00255 1/20 0.52
USP2 O75604 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29451340 1.00 HPRT1 (1.00) HPRT1ALDH1A1HSD17B10TSHRTDP1
SCHEMBL31177955 1.00 HPRT1 (1.00) HPRT1ALDH1A1HSD17B10TSHRTDP1
Chrysene SCHEMBL29792076 1.00 HPRT1 (1.00) HPRT1ALDH1A1HSD17B10TSHRTDP1
SCHEMBL29640482 1.00 HPRT1 (1.00) HPRT1ALDH1A1HSD17B10TSHRTDP1
Chrysene SCHEMBL384031 1.00 HPRT1 (1.00) HPRT1ALDH1A1HSD17B10TSHRTDP1
Chrysene SCHEMBL29355502 1.00 HPRT1 (1.00) HPRT1ALDH1A1HSD17B10TSHRTDP1
Chrysene SCHEMBL30433768 1.00 HPRT1 (1.00) HPRT1ALDH1A1HSD17B10TSHRTDP1
SCHEMBL25510 1.00 HPRT1 (1.00) HPRT1ALDH1A1HSD17B10TSHRTDP1
Chrysene SCHEMBL27115 1.00 HPRT1 (1.00) HPRT1ALDH1A1HSD17B10TSHRTDP1
Triphenylene SCHEMBL10448508 1.00 HPRT1 (1.00) HPRT1ALDH1A1HSD17B10TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4988446-A QUANTITATIVE ANALYSIS BY CHROMATOGRAPHY OF HYDROCARBON OILS, UV RADIATION EXXON RESEARCH AND ENGINEERING COMPANY (US) 1991-01-29 US disclosed