Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.72 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.67 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.67 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.67 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | FAAH | O00519 | 2/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10741431 | 0.98 | EPHX2 (0.75) | EPHX2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21998923 | 0.98 | EPHX2 (0.75) | EPHX2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9787410 | 0.98 | EPHX2 (0.75) | EPHX2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9787431 | 0.98 | EPHX2 (0.75) | EPHX2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9787358 | 0.98 | EPHX2 (0.75) | EPHX2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9787405 | 0.98 | EPHX2 (0.75) | EPHX2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9787468 | 0.97 | EPHX2 (0.73) | EPHX2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9787297 | 0.89 | CYP3A4 (0.64) | EPHX2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3809498 | 0.89 | EPHX2 (0.84) | EPHX2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27760616 | 0.86 | EPHX2 (0.58) | EPHX2HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4689182-A | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity | WARNER-LAMBERT COMPANY (US) | 1987-08-25 | — | — | US | claimed |
| CN-86108626-A | Phenylformic acid and benzoate derivatives with anti-inflammatory and pain palliation efficacy | — | 1987-07-22 | — | — | CN | claimed |
| EP-0226223-A2 | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity | WARNER-LAMBERT COMPANY (US) | 1987-06-24 | — | — | EP | claimed |
| US-5002703-A | Benzoic acid and benzoic acid ester derivatives having antiinflammatory and analgesic activity | WARNER-LAMBERT COMPANY (US) | 1991-03-26 | — | — | US | disclosed |
| US-4990533-A | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity | WARNER-LAMBERT CO. (US) | 1991-02-05 | — | — | US | disclosed |
| US-4980095-A | Sodium salt of N-C4-carboxybenzyl nonanamide | WARNER-LAMBERT COMPANY (US) | 1990-12-25 | — | — | US | disclosed |
| US-4771064-A | Benzoic acid and benzoic acid ester derivatives having antiflammatory and analgesic activity | WARNER-LAMBERT COMPANY (US) | 1988-09-13 | — | — | US | disclosed |
| US-4755518-A | Imidazolyl or tetrazolyl substituted benzoic acid derivatives and pharmaceutical compositions thereof | WARNER-LAMBERT COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| US-4719232-A | Benzoic acid and benzoic acid ester derivatives to treat headaches | WARNER-LAMBERT COMPANY (US) | 1988-01-12 | — | — | US | disclosed |
| US-4719234-A | Benzoic acid and benzoic acid ester derivatives to treat inflammation | WARNER-LAMBERT COMPANY (US) | 1988-01-12 | — | — | US | disclosed |
| US-4719233-A | Benzoic acid and benzoic acid ester derivatives to treat pain | WARNER-LAMBERT COMPANY (US) | 1988-01-12 | — | — | US | disclosed |
| US-4689182-A | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity | WARNER-LAMBERT COMPANY (US) | 1987-08-25 | — | — | US | disclosed |
| CN-86108626-A | Phenylformic acid and benzoate derivatives with anti-inflammatory and pain palliation efficacy | — | 1987-07-22 | — | — | CN | disclosed |
| EP-0226223-A2 | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity | WARNER-LAMBERT COMPANY (US) | 1987-06-24 | — | — | EP | disclosed |