Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787900 | 1.00 | CNR2 (0.36) | CNR2KCNN4CNR1 | |
| SCHEMBL19224098 | 1.00 | CNR2 (0.36) | CNR2KCNN4CNR1 | |
| SCHEMBL29733340 | 0.93 | KCNN4 (0.37) | CNR2KCNN4 | |
| SCHEMBL19224174 | 0.90 | CNR2 (0.35) | CNR2CNR1 | |
| SCHEMBL19223639 | 0.90 | CNR2 (0.35) | CNR2CNR1 | |
| SCHEMBL959232 | 0.86 | KCNN4 (0.35) | KCNN4 | |
| SCHEMBL381339 | 0.86 | KCNN4 (0.35) | KCNN4 | |
| SCHEMBL30670324 | 0.85 | KCNN4 (0.39) | KCNN4 | |
| SCHEMBL9003862 | 0.84 | KCNN4 (0.36) | KCNN4 | |
| SCHEMBL19223923 | 0.83 | KCNN4 (0.33) | KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030629-A | Transdermal Administration Of Cardiovascular Agents | THERAPEUTIC PATCH RESEARCH N.V. | 1991-07-09 | — | — | US | disclosed |
| US-4876249-A | TOPICAL; TRANSDERMAL, SYSTEMIC; FLUOCINOLINE ACETONIDE AND IMIDAZOLINE OR OXAZOLINE PENETRATION ENHANCER MIXTURE; THERAPEUTIC DRUGS | THERAPEUTIC PATCH RESEARCH N.V. | 1989-10-24 | — | — | US | disclosed |
| EP-0296199-A1 | HETEROCYCLIC COMPOUNDS FOR TRANSDERMAL USE | RAJADHYAKSHA, Vithal J. (US) | 1988-12-28 | — | — | EP | disclosed |
| WO-1988004938-A1 | HETEROCYCLIC COMPOUNDS FOR TRANSDERMAL USE | RAJADHYAKSHA VITHAL J (US) | 1988-07-14 | — | — | WO | disclosed |