Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | TACR1 | P25103 | 3/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788249 | 0.79 | CYP2C19 (0.38) | KDM4EL3MBTL1 | |
| SCHEMBL9788219 | 0.79 | POLB (0.54) | TSHRKDM4EPOLBCA1KMT2A | |
| SCHEMBL9788180 | 0.77 | POLB (0.46) | TSHRKDM4EPOLBCA1TACR1 | |
| SCHEMBL21239582 | 0.73 | TSHR (0.48) | TSHRKDM4EPOLBCA1TACR1 | |
| SCHEMBL10762456 | 0.73 | CA1 (0.40) | TSHRCA1TACR1KMT2ACA2 | |
| SCHEMBL9788254 | 0.73 | CA1 (0.38) | TSHRKDM4EPOLBCA1TACR1 | |
| SCHEMBL9788255 | 0.72 | KDM4E (0.47) | TSHRKDM4EPOLBCA1KMT2A | |
| SCHEMBL9788163 | 0.72 | POLB (0.38) | TSHRKDM4EPOLBCA1TACR1 | |
| SCHEMBL11146323 | 0.72 | TSHR (0.67) | TSHRKDM4EPOLBCA1TACR1 | |
| SCHEMBL9788141 | 0.69 | SMN1; SMN2 (0.45) | POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985582-A | CHEMICAL INTERMEDIATES FOR BICYCLIC RING COMPOUNDS HAVING MULTIPLE SULFUR ATOMS IN THE RING SYSTEM | THE WELLCOME FOUNDATION LTD. (GB) | 1991-01-15 | — | — | US | disclosed |
| EP-0216625-A2 | Pesticidal compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-04-01 | — | — | EP | disclosed |