Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.75 |
| ▸ | DGKA | P23743 | 1/20 | 0.75 |
| ▸ | DGKG | P49619 | 1/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.66 |
| ▸ | HTR2A | P28223 | 4/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | DRD2 | P14416 | 2/20 | 0.64 |
| ▸ | HTR2C | P28335 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.64 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.64 |
| ▸ | DRD1 | P21728 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9788298 | 0.99 | MAPT (0.74) | MAPTHIF1ADGKADGKGKCNH2 | |
| SCHEMBL9788314 | 0.87 | MAPT (0.58) | MAPTHIF1ADGKADGKGKCNH2 | |
| Hydrochloric Acid SCHEMBL9631329 | 0.86 | MAPT (0.57) | MAPTHIF1ADGKADGKGKCNH2 | |
| Diacylglycerol Kinase Inhibitor Ii SCHEMBL317664 | 0.86 | MAPT (1.00) | MAPTHIF1ADGKADGKGKCNH2 | |
| SCHEMBL10471414 | 0.83 | MAPT (0.62) | MAPTHIF1ADGKADGKGKCNH2 | |
| SCHEMBL10565826 | 0.82 | MAPT (0.61) | MAPTHIF1ADGKADGKGKCNH2 | |
| Hydrochloric Acid SCHEMBL9870098 | 0.78 | HTR2A (0.91) | MAPTHIF1AKCNH2HTR2ACYP3A4 | |
| SCHEMBL10564987 | 0.78 | MAPT (0.56) | MAPTHIF1ADGKADGKGKCNH2 | |
| Ketanserin SCHEMBL4862503 | 0.78 | HTR2A (1.00) | MAPTHIF1AKCNH2HTR2ACYP3A4 | |
| SCHEMBL10566646 | 0.78 | MAPT (0.58) | MAPTHIF1ADGKADGKGKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071847-A | BIS (ARYL) ALKENE COMPOUNDS OF HOMOPIPERIDINES USEFUL AS SEROTONIN-ANTAGONISTS | ADIR ET COMPAGNIE (FR) | 1991-12-10 | — | — | US | claimed |