Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11582596 | 1.00 | PLCG1 (0.79) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL9788374 | 1.00 | PLCG1 (0.79) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11582598 | 1.00 | PLCG1 (0.79) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11182332 | 0.94 | PLCG1 (0.85) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11411669 | 0.94 | PLCG1 (0.85) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11411672 | 0.94 | PLCG1 (0.85) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11182329 | 0.94 | PLCG1 (0.85) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL15705828 | 0.92 | PLCG1 (0.68) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL15705994 | 0.91 | PLCG1 (0.66) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL11578082 | 0.91 | PLCG1 (0.66) | PLCG1ALDH1A1L3MBTL1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043439-A | Alkylation; organo-copper reagents; 3-hydrocarbon substitution ; antibiotics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-08-27 | — | — | US | disclosed |
| US-4931555-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-06-05 | — | — | US | disclosed |
| US-4435321-A | BACTERICIDES AND INTERMEDIATES FOR 2- OR 3-CEPHEMS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |
| US-4410458-A | GROUP 5B OR 6B METAL COMPOUND OXIDATION CATALYST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-10-18 | — | — | US | disclosed |
| US-4267340-A | BACTERICIDES; SYNTHESIS OF PENICILLINS AND CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-05-12 | — | — | US | disclosed |
| US-4071527-A | Certain benzothiazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-01-31 | — | — | US | disclosed |
| US-3993646-A | Process for the ring expansion of penicillins to cephalosporin compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-11-23 | — | — | US | disclosed |