Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9296161 | 1.00 | KAT8 (0.55) | KAT8ALDH1A1HPGDHSD17B10PTGS2 | |
| SCHEMBL17342938 | 0.86 | MAPT (0.53) | KAT8ALDH1A1HPGDPTGS2MAPT | |
| SCHEMBL23064868 | 0.85 | KAT8 (0.50) | KAT8ALDH1A1HPGDHSD17B10PTGS2 | |
| SCHEMBL9295201 | 0.85 | KAT8 (0.50) | KAT8ALDH1A1HPGDHSD17B10PTGS2 | |
| SCHEMBL247053 | 0.83 | MAPT (0.61) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL10078302 | 0.83 | MAPT (0.61) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL305089 | 0.83 | MAPT (0.61) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL14488588 | 0.79 | MAPT (0.52) | KAT8ALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL19651990 | 0.79 | KAT8 (0.55) | KAT8ALDH1A1HPGDHSD17B10PTGS2 | |
| SCHEMBL9524415 | 0.77 | KDM4E (0.67) | KAT8ALDH1A1HPGDHSD17B10PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075192-A | For relief printing plates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-12-24 | — | — | US | disclosed |
| US-4956252-A | ACID MODIFIED COPOLYMER CORE SHELL, AN ADDITION PHOTOPOLYMERIZABLE MONOMER, PHOTOINITIATOR FOR FLEXOGRAPHY | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1990-09-11 | — | — | US | disclosed |