Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7017524 | 1.00 | NPSR1 (0.46) | NPSR1KMT2AMEN1DRD4BCHE | |
| SCHEMBL9531494 | 1.00 | NPSR1 (0.46) | NPSR1KMT2AMEN1DRD4BCHE | |
| SCHEMBL4481162 | 1.00 | NPSR1 (0.46) | NPSR1KMT2AMEN1DRD4BCHE | |
| SCHEMBL4481166 | 1.00 | NPSR1 (0.46) | NPSR1KMT2AMEN1DRD4BCHE | |
| Hydrochloric Acid SCHEMBL10690431 | 0.99 | NPSR1 (0.45) | NPSR1KMT2AMEN1DRD4BCHE | |
| Hydrochloric Acid SCHEMBL10690440 | 0.99 | NPSR1 (0.45) | NPSR1KMT2AMEN1DRD4BCHE | |
| Hydrochloric Acid SCHEMBL9790154 | 0.99 | NPSR1 (0.45) | NPSR1KMT2AMEN1DRD4BCHE | |
| Hydrochloric Acid SCHEMBL10690436 | 0.99 | NPSR1 (0.45) | NPSR1KMT2AMEN1DRD4BCHE | |
| SCHEMBL4484399 | 0.89 | NPSR1 (0.46) | NPSR1KMT2AMEN1DRD4BCHE | |
| SCHEMBL4484395 | 0.89 | NPSR1 (0.46) | NPSR1KMT2AMEN1DRD4BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990521-A | Treating diarhea | JANSSEN PHARMACEUTICA (BE) | 1991-02-05 | — | — | US | disclosed |