Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 17/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9792139 | 1.00 | PTGDR (0.40) | PTGDRTBXA2RCTSLCTSKTBXAS1 | |
| SCHEMBL9533880 | 0.90 | PTGDR (0.39) | PTGDRTBXA2RTBXAS1PTGIR | |
| SCHEMBL9533893 | 0.90 | PTGDR (0.39) | PTGDRTBXA2RTBXAS1PTGIR | |
| SCHEMBL9536058 | 0.90 | TBXA2R (0.47) | PTGDRTBXA2RTBXAS1PTGIR | |
| SCHEMBL9536070 | 0.90 | TBXA2R (0.47) | PTGDRTBXA2RTBXAS1PTGIR | |
| SCHEMBL9792070 | 0.85 | PTGDR (0.49) | PTGDRTBXA2RTBXAS1PTGIR | |
| SCHEMBL9792062 | 0.85 | PTGDR (0.49) | PTGDRTBXA2RTBXAS1PTGIR | |
| SCHEMBL9535130 | 0.77 | TBXA2R (0.64) | PTGDRTBXA2RTBXAS1PTGIR | |
| SCHEMBL10430072 | 0.77 | TBXA2R (0.64) | PTGDRTBXA2RTBXAS1PTGIR | |
| SCHEMBL9535728 | 0.77 | TBXA2R (0.64) | PTGDRTBXA2RTBXAS1PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002972-A | Compound and composition of substituted hexenoic acid derivatives useful for treating thromboxane A2 mediated diseases | SHIONOGI & CO., LTD. (JP) | 1991-03-26 | — | — | US | disclosed |