SCHEMBL97939

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8827593	1.00	TSHR (0.64)	TSHRTRPV1FAAHESR1ADRA2A
	SCHEMBL28582196	0.96	TSHR (0.58)	TSHRTRPV1FAAHESR1ADRA2A
	SCHEMBL15189293	0.92	ESR1 (0.57)	TSHRTRPV1ESR1ADRA2AADORA3
	SCHEMBL5252411	0.90	ESR1 (0.53)	ESR1ADRA2AADORA3TACR2SLC6A2
	SCHEMBL5074036	0.88	TSHR (0.54)	TSHRTRPV1FAAHESR1ADRA2A
	SCHEMBL1667016	0.87	MEN1 (0.57)	TSHRALDH1A1LMNATP53CYP3A4
	SCHEMBL7349079	0.87	MEN1 (0.57)	TSHRALDH1A1LMNATP53CYP3A4
	SCHEMBL11204532	0.86	TAAR1 (0.45)	TSHRTRPV1FAAHESR1ADRA2A
	SCHEMBL28400146	0.86	ESR1 (0.59)	TRPV1FAAHESR1ADRA2AADORA3
	SCHEMBL11141986	0.86	ESR1 (0.59)	TRPV1FAAHESR1ADRA2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.