Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | AHR | P35869 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 5/20 | 0.51 |
| ▸ | HTR2C | P28335 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | HTR6 | P50406 | 3/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | HTR1D | P28221 | 2/20 | 0.51 |
| ▸ | HTR1B | P28222 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73842 | 0.85 | MEN1 (0.62) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL8699685 | 0.82 | MEN1 (0.58) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL4100216 | 0.82 | MEN1 (0.58) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL27452680 | 0.82 | MEN1 (0.58) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL30354035 | 0.82 | MEN1 (0.58) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL22879441 | 0.82 | MEN1 (0.58) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL12413778 | 0.81 | MEN1 (0.56) | MEN1KMT2ACYP3A4MAPTAHR | |
| Hydrochloric Acid SCHEMBL27797436 | 0.81 | PMP22 (0.57) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL19134737 | 0.79 | MEN1 (0.55) | MEN1KMT2ACYP3A4MAPTAHR | |
| SCHEMBL10145510 | 0.79 | MEN1 (0.59) | MEN1KMT2ACYP3A4MAPTAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977274-A | REACTING PROTECTED GLYCIDYLOXYINDOLE WITH AMINE, DEPROTECTING | SANOFI (FR) | 1990-12-11 | — | — | US | claimed |
| EP-0338352-A2 | Salicylic acid derivatives | MERCK PATENT GmbH (DE) | 1989-10-25 | — | — | EP | claimed |
| EP-0228356-B1 | HYDROXY-4-INDOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | SANOFI S.A. (FR) | 1989-08-02 | — | — | EP | claimed |
| US-4987133-A | Salicylic acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-22 | — | — | US | disclosed |
| US-4977274-A | REACTING PROTECTED GLYCIDYLOXYINDOLE WITH AMINE, DEPROTECTING | SANOFI (FR) | 1990-12-11 | — | — | US | disclosed |
| EP-0338352-A3 | SALICYLIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |
| EP-0338352-A2 | Salicylic acid derivatives | MERCK PATENT GmbH (DE) | 1989-10-25 | — | — | EP | disclosed |
| EP-0338352-A2 | Salicylic acid derivatives | MERCK PATENT GmbH (DE) | 1989-10-25 | — | — | EP | disclosed |