Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.52 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 2/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | FABP2 | P12104 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375685 | 0.92 | RARB (0.52) | RARBRARARARGGCGRGPR3 | |
| SCHEMBL10980255 | 0.90 | RARB (0.60) | RARBRARARARGGPR3HTR2A | |
| SCHEMBL8375674 | 0.90 | RARB (0.50) | RARBRARARARGGCGRGPR3 | |
| SCHEMBL10981775 | 0.89 | RARB (0.63) | RARBRARARARGGPR3HTR2A | |
| SCHEMBL10976869 | 0.89 | RARB (0.63) | RARBRARARARGGPR3HTR2A | |
| SCHEMBL15851250 | 0.89 | RARB (0.59) | RARBRARARARGGPR3HTR2A | |
| SCHEMBL10978328 | 0.89 | RARB (0.63) | RARBRARARARGGPR3HTR2A | |
| SCHEMBL9663450 | 0.88 | RARB (0.61) | RARBRARARARGGPR3HTR2A | |
| SCHEMBL9664830 | 0.88 | RARB (0.61) | RARBRARARARGGPR3HTR2A | |
| SCHEMBL9663332 | 0.86 | RARB (0.64) | RARBRARARARGGPR3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407569-A1 | DIPHENYLETHANES | MERCK PATENT GmbH (DE) | 1991-01-16 | — | — | EP | disclosed |