Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | PPID | Q08752 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619371 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2POLBMEN1KMT2AHSD11B1 | |
| SCHEMBL312831 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2POLBMEN1KMT2AHSD11B1 | |
| SCHEMBL312832 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2POLBMEN1KMT2AHSD11B1 | |
| SCHEMBL313012 | 0.79 | POLB (0.55) | SMN1; SMN2POLBMEN1KMT2AHSD11B1 | |
| SCHEMBL5972813 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2POLBMEN1KMT2AHSD11B1 | |
| SCHEMBL10906532 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBMEN1KMT2AHSD11B1 | |
| SCHEMBL4793126 | 0.78 | CYP2C19 (0.52) | SMN1; SMN2MEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL314150 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBMEN1KMT2AHSD11B1 | |
| SCHEMBL10284966 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBMEN1KMT2AHSD11B1 | |
| SCHEMBL314148 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBMEN1KMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999451-A | Process for preparing dihalovinylcyclopropanecarboxylates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-03-12 | — | — | US | disclosed |
| US-4833266-A | Process for preparing dihalovinylcyclopropanecarboxylates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-05-23 | — | — | US | disclosed |
| US-4681953-A | Process for preparing dihalovinylcyclopropanecarboxylates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1987-07-21 | — | — | US | disclosed |
| US-4454343-A | Intermediates in a process for preparing dihalovinylcyclopropanecarboxylates | FMC CORPORATION (US) | 1984-06-12 | — | — | US | disclosed |
| US-4214097-A | Process for preparing dihalovinylcyclopropanecarboxylates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1980-07-22 | — | — | US | disclosed |