Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.44 |
| ▸ | TERT | O14746 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | TOP1 | P11387 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422102 | 1.00 | EPHX2 (0.44) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL7551976 | 1.00 | EPHX2 (0.44) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL9504341 | 0.92 | GGPS1 (0.41) | PPARDMAPTMMP2 | |
| SCHEMBL9500709 | 0.92 | GGPS1 (0.41) | PPARDMAPTMMP2 | |
| SCHEMBL9500708 | 0.92 | GGPS1 (0.41) | PPARDMAPTMMP2 | |
| SCHEMBL7109928 | 0.92 | GGPS1 (0.41) | PPARDMAPTMMP2 | |
| SCHEMBL9504351 | 0.92 | GGPS1 (0.41) | PPARDMAPTMMP2 | |
| SCHEMBL9388449 | 0.92 | GGPS1 (0.41) | PPARDMAPTMMP2 | |
| SCHEMBL9388470 | 0.90 | GGPS1 (0.39) | MAPTMMP2 | |
| SCHEMBL29100577 | 0.79 | EPHX2 (0.47) | EPHX2TERTPTPN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413700-A1 | NEW ALKYLPHOSPHONO- AND PHOSPHOSERINES, METHOD FOR PREPARING THEM, AND PHARMACEUTICAL SUBSTANCES CONTAINING THEM | Hafslund Nycomed Pharma Aktiengesellschaft (AT) | 1991-02-27 | — | — | EP | disclosed |
| WO-1989010370-A1 | NEW ALKYLPHOSPHONO- AND PHOSPHOSERINES, METHOD FOR PREPARING THEM, AND PHARMACEUTICAL SUBSTANCES CONTAINING THEM | CL-PHARMA AKTIENGESELLSCHAFT (AT) | 1989-11-02 | — | — | WO | disclosed |
| EP-0338407-A1 | New alkylphosphonoserines, methods for preparing them, and pharmaceutical substances containing them | Hafslund Nycomed Pharma Aktiengesellschaft (AT) | 1989-10-25 | — | — | EP | disclosed |