Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 16/20 | 0.66 |
| ▸ | TK1 | P04183 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | EDNRA | P25101 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | HBB | P68871 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17186373 | 0.99 | PNP (0.65) | PNPTK1USP2TSHREDNRA | |
| Hydrochloric Acid SCHEMBL17186289 | 0.87 | PNP (0.56) | PNPTK1USP2TSHREDNRA | |
| SCHEMBL4967486 | 0.81 | PNP (0.59) | PNPTK1USP2TSHREDNRA | |
| SCHEMBL18249 | 0.80 | PNP (1.00) | PNPTK1 | |
| SCHEMBL21629986 | 0.80 | PNP (0.58) | PNPTK1USP2TSHREDNRA | |
| SCHEMBL9798305 | 0.80 | PNP (0.61) | PNPTK1USP2TSHREDNRA | |
| SCHEMBL4966181 | 0.79 | PNP (0.64) | PNPTK1USP2TSHREDNRA | |
| SCHEMBL9665264 | 0.79 | PNP (1.00) | PNPUSP2TSHRHSD17B10 | |
| SCHEMBL9700023 | 0.79 | PNP (0.60) | PNP | |
| SCHEMBL9799097 | 0.79 | PNP (0.60) | PNPTK1USP2TSHREDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4772606-A | AUTOIMMUNE DISEASES, ORGAN TRANSPLANTS | WARNER-LAMBERT COMPANY (US) | 1988-09-20 | — | — | US | claimed |
| CN-113717174-B | Tumor targeting drug resistant O6-thienylmethylguanine-indoloquinone-chloroethylnitrosourea combined molecule and preparation method thereof | 北京工业大学 | 2022-07-12 | — | — | CN | disclosed |
| CN-113730595-A | Multifunctional nano-carrier with drug resistance and dual responsiveness of hypoxia/glutathione and preparation method and application thereof | 北京工业大学 | 2021-12-03 | — | — | CN | disclosed |
| CN-113730595-A | Multifunctional nano-carrier with drug resistance and dual responsiveness of hypoxia/glutathione and preparation method and application thereof | 北京工业大学 | 2021-12-03 | — | — | CN | disclosed |
| CN-113717174-A | Tumor targeting drug resistant O6-thienylmethylguanine-indoloquinone-chloroethylnitrosourea combined molecule and preparation method thereof | 北京工业大学 | 2021-11-30 | — | — | CN | disclosed |
| US-5051429-A | For treatment of autoimmune diseases such as arthritis, lupus, antiinflammatory agents, multiple sclerosis, diabetes and viral diseases | WARNER-LAMBERT CO. (US) | 1991-09-24 | — | — | US | disclosed |
| US-4952693-A | TREATING AUTOIMMUNE DISEASES | WARNER-LAMBERT COMPANY (US) | 1990-08-28 | — | — | US | disclosed |
| US-4772606-A | AUTOIMMUNE DISEASES, ORGAN TRANSPLANTS | WARNER-LAMBERT COMPANY (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0178178-A2 | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1986-04-16 | — | — | EP | disclosed |