Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 8/20 | 0.63 |
| ▸ | CTSH | P09668 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9798675 | 1.00 | CTSC (0.63) | CTSCCTSHCTSKCYP1A2CYP3A4 | |
| SCHEMBL2182283 | 0.92 | CTSC (0.60) | CTSCCTSHCTSKCYP1A2CYP3A4 | |
| SCHEMBL9225086 | 0.89 | CTSC (0.66) | CTSCCTSHCTSKCYP1A2CYP3A4 | |
| SCHEMBL9144573 | 0.87 | CTSC (0.76) | CTSCCTSHCTSKCYP1A2CYP3A4 | |
| SCHEMBL583122 | 0.87 | CTSC (0.76) | CTSCCTSHCTSKCYP1A2CYP3A4 | |
| SCHEMBL1691349 | 0.87 | CTSC (0.76) | CTSCCTSHCTSKCYP1A2CYP3A4 | |
| SCHEMBL583121 | 0.87 | CTSC (0.76) | CTSCCTSHCTSKCYP1A2CYP3A4 | |
| SCHEMBL9389290 | 0.87 | CTSC (0.76) | CTSCCTSHCTSKCYP1A2CYP3A4 | |
| SCHEMBL11443315 | 0.86 | CTSC (0.63) | CTSCCTSHCTSKCYP1A2CYP3A4 | |
| SCHEMBL4588611 | 0.86 | CTSC (0.74) | CTSCCTSHCTSKCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030732-A | Antiacterial agents | MERCK & CO., INC. (US) | 1991-07-09 | — | — | US | disclosed |
| EP-0282219-B1 | AMINOETHYLPHOSPHINIC ACID DERIVATIVES | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1991-07-03 | — | — | EP | disclosed |
| EP-0282219-A1 | Aminoethylphosphinic acid derivatives | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1988-09-14 | — | — | EP | disclosed |