Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HMGCR | P04035 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726787 | 0.83 | HSD17B10 (0.43) | HSD17B10USP2HMGCRKDM4EALDH1A1 | |
| SCHEMBL9726603 | 0.74 | HSD17B10 (0.38) | HSD17B10USP2KDM4EALDH1A1HPGD | |
| SCHEMBL9726839 | 0.73 | HSD17B10 (0.41) | HSD17B10USP2HMGCRKDM4EALDH1A1 | |
| SCHEMBL9726834 | 0.73 | HSD17B10 (0.41) | HSD17B10USP2HMGCRKDM4EALDH1A1 | |
| SCHEMBL9726533 | 0.73 | HMGCR (0.55) | HSD17B10USP2HMGCRALDH1A1 | |
| SCHEMBL9726806 | 0.73 | HMGCR (0.43) | HSD17B10USP2HMGCRALDH1A1HPGD | |
| SCHEMBL9726484 | 0.71 | HMGCR (0.43) | HMGCRHPGD | |
| SCHEMBL9726705 | 0.69 | HMGCR (0.52) | HMGCRALDH1A1GAA | |
| SCHEMBL9726690 | 0.69 | HMGCR (0.52) | HMGCRALDH1A1GAA | |
| SCHEMBL9726697 | 0.69 | HMGCR (0.52) | HMGCRALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068346-A | Anticholesterol agents | BRISTOL-MYERS COMPANY (US) | 1991-11-26 | — | — | US | disclosed |