Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10608540 | 1.00 | HMGCR (0.62) | HMGCR | |
| SCHEMBL9799128 | 1.00 | HMGCR (0.62) | HMGCR | |
| SCHEMBL9726639 | 0.89 | HMGCR (0.64) | HMGCR | |
| SCHEMBL9726642 | 0.89 | HMGCR (0.64) | HMGCR | |
| SCHEMBL9726525 | 0.89 | HMGCR (0.49) | HMGCR | |
| SCHEMBL9726522 | 0.89 | HMGCR (0.49) | HMGCR | |
| SCHEMBL9726530 | 0.89 | HMGCR (0.49) | HMGCR | |
| SCHEMBL9726842 | 0.87 | HMGCR (0.68) | HMGCR | |
| SCHEMBL9726845 | 0.87 | HMGCR (0.68) | HMGCR | |
| SCHEMBL9726760 | 0.87 | HMGCR (0.68) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068346-A | Anticholesterol agents | BRISTOL-MYERS COMPANY (US) | 1991-11-26 | — | — | US | claimed |