SCHEMBL9799158

SCHEMBL9799158

Cc1cccc(CCCc2ccc(N)cc2)c1

nearest known ligand 0.63

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.63
CYP19A1 P11511 1/20 0.58
MAOB P27338 6/20 0.57
MAOA P21397 4/20 0.50
IDO1 P14902 2/20 0.47
HTR2A P28223 1/20 0.47
GFER P55789 1/20 0.46
NOS3 P29474 1/20 0.45
NOS1 P29475 1/20 0.45
NOS2 P35228 1/20 0.45
HRH3 Q9Y5N1 1/20 0.45
ALDH1A1 P00352 1/20 0.44
ACHE P22303 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25128819 0.92 CYP19A1 (0.68) TAAR1CYP19A1MAOBMAOAIDO1
SCHEMBL9799117 0.87 TAAR1 (0.60) TAAR1CYP19A1MAOBMAOAIDO1
SCHEMBL2913956 0.86 CYP19A1 (0.69) CYP19A1MAOBMAOAHTR2AGFER
SCHEMBL8099771 0.86 TAAR1 (0.68) TAAR1IDO1HRH3ACHE
SCHEMBL3016081 0.84 TAAR1 (0.61) TAAR1IDO1HTR2ANOS3NOS1
SCHEMBL31500446 0.84 TAAR1 (0.61) TAAR1IDO1HTR2ANOS3NOS1
SCHEMBL841378 0.82 CYP19A1 (0.84) CYP19A1MAOBMAOAHTR2AGFER
SCHEMBL8092500 0.82 TAAR1 (0.68) TAAR1IDO1HRH3ACHE
SCHEMBL9799262 0.81 CYP19A1 (0.63) TAAR1CYP19A1MAOBMAOAHTR2A
SCHEMBL20067936 0.81 TAAR1 (0.57) TAAR1CYP19A1MAOBMAOAIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5015762-A Alkoxy substituted ureas as herbicides BASF AKTIENGESELLSCHAFT (DE) 1991-05-14 US disclosed
EP-0269041-B1 FUNGICIDAL CYCLOHEXYLAMINES BASF Aktiengesellschaft (DE) 1991-04-10 EP disclosed
US-4968676-A PLANTS, SOILS, SEEDS BASF AKTIENGESELLSCHAFT (DE) 1990-11-06 US disclosed
US-4897425-A Fungicidal cyclohexylamines BASF AKTIENGESELLSCHAFT (DE) 1990-01-30 US disclosed
EP-0269041-A2 Fungicidal cyclohexylamines BASF Aktiengesellschaft (DE) 1988-06-01 EP disclosed
EP-0041145-B1 ARALKYL-PHENYL UREAS AND THEIR HERBICIDAL COMPOSITIONS BASF Aktiengesellschaft (DE) 1984-12-19 EP disclosed
US-4422871-A Aralkylphenylureas and herbicides containing these BASF AKTIENGESELLSCHAFT (DE) 1983-12-27 US disclosed
EP-0041145-A2 Aralkyl-phenyl ureas and their herbicidal compositions BASF Aktiengesellschaft (DE) 1981-12-09 EP disclosed