Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799162 | 1.00 | HMGCR (0.51) | HMGCRALDH1A1RAB9ASMN1; SMN2POLB | |
| SCHEMBL9726642 | 0.90 | HMGCR (0.64) | HMGCR | |
| SCHEMBL9726639 | 0.90 | HMGCR (0.64) | HMGCR | |
| SCHEMBL9726496 | 0.90 | HMGCR (0.54) | HMGCRALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9726485 | 0.90 | HMGCR (0.54) | HMGCRALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9798888 | 0.86 | HMGCR (0.60) | HMGCRALDH1A1 | |
| SCHEMBL9798880 | 0.86 | HMGCR (0.60) | HMGCRALDH1A1 | |
| SCHEMBL9726503 | 0.85 | HMGCR (0.52) | HMGCR | |
| SCHEMBL9726510 | 0.85 | HMGCR (0.52) | HMGCR | |
| SCHEMBL9726495 | 0.85 | HMGCR (0.52) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068346-A | Anticholesterol agents | BRISTOL-MYERS COMPANY (US) | 1991-11-26 | — | — | US | claimed |
| WO-1988006584-A1 | ANTIHYPERCHOLESTEROLEMIC TETRAZOLE COMPOUNDS | BRISTOL-MYERS COMPANY (US) | 1988-09-07 | — | — | WO | claimed |