Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799369 | 0.96 | MEN1 (0.44) | TSHRMAPK1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL9799096 | 0.96 | MEN1 (0.44) | TSHRMAPK1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL399170 | 0.86 | TSHR (0.45) | TSHRMAPK1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL3084586 | 0.82 | MEN1 (0.52) | TSHRMAPK1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL7809336 | 0.82 | MEN1 (0.52) | TSHRMAPK1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL7809339 | 0.82 | MEN1 (0.52) | TSHRMAPK1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL7808059 | 0.82 | MEN1 (0.52) | TSHRMAPK1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL246408 | 0.80 | TSHR (0.39) | TSHRMAPK1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL28148988 | 0.77 | — | — | |
| SCHEMBL25113585 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030754-A | Hydroxy-terminated substituted diurea derivatives | TEXACO CHEMICAL COMPANY (US) | 1991-07-09 | — | — | US | disclosed |