Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.56 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.50 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.50 |
| ▸ | CCND1 | P24385 | 1/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | CDK7 | P50613 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | CCNH | P51946 | 1/20 | 0.50 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5838349 | 0.82 | NPC1 (0.59) | PLAUCCNT1CCNB2CCNE2CDK1 | |
| SCHEMBL24213305 | 0.82 | NPC1 (0.59) | PLAUCCNT1CCNB2CCNE2CDK1 | |
| SCHEMBL5838346 | 0.82 | NPC1 (0.59) | PLAUCCNT1CCNB2CCNE2CDK1 | |
| SCHEMBL13021483 | 0.82 | PLAU (0.55) | PLAUCCNT1CCNB2CCNE2CDK1 | |
| SCHEMBL9275769 | 0.82 | PLAU (0.59) | PLAUCCNT1CCNB2CCNE2CDK1 | |
| SCHEMBL9801446 | 0.82 | PLAU (0.59) | PLAUCCNT1CCNB2CCNE2CDK1 | |
| SCHEMBL3184824 | 0.80 | PLAU (0.62) | PLAUCCNT1CCNB2CCNE2CDK1 | |
| SCHEMBL1263552 | 0.80 | PLAU (0.53) | PLAUCCNT1CCNB2CCNE2CDK1 | |
| SCHEMBL1263553 | 0.80 | PLAU (0.53) | PLAUCCNT1CCNB2CCNE2CDK1 | |
| Charcoal, Activated SCHEMBL5133893 | 0.79 | PLAU (0.51) | PLAUCCNT1CCNB2CCNE2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978074-A | CATALYTIC HYDROGENATION | UNIROYAL INC. (US) | 1976-08-31 | — | — | US | claimed |
| EP-0419412-A2 | Process for the preparation of benzotriazoles | CIBA-GEIGY AG (CH) | 1991-03-27 | — | — | EP | disclosed |