Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9802623 | 1.00 | CYP2C19 (0.44) | CYP2C19GSK3BSMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL9802177 | 1.00 | CYP2C19 (0.44) | CYP2C19GSK3BSMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL9802609 | 1.00 | CYP2C19 (0.44) | CYP2C19GSK3BSMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL9802168 | 1.00 | CYP2C19 (0.44) | CYP2C19GSK3BSMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL9802421 | 0.91 | CACNA1C (0.41) | CYP2C19GSK3BSMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL9802081 | 0.86 | GSK3B (0.40) | CYP2C19GSK3BLMNAMAPTMEN1 | |
| SCHEMBL9802096 | 0.86 | GSK3B (0.40) | CYP2C19GSK3BLMNAMAPTMEN1 | |
| SCHEMBL9802072 | 0.86 | GSK3B (0.40) | CYP2C19GSK3BLMNAMAPTMEN1 | |
| SCHEMBL9802375 | 0.86 | GSK3B (0.40) | CYP2C19GSK3BLMNAMAPTMEN1 | |
| SCHEMBL9802389 | 0.86 | GSK3B (0.40) | CYP2C19GSK3BLMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055464-A | Cognition activators, diuretics, antiulcer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1991-10-08 | — | — | US | disclosed |
| EP-0322779-A2 | Benzolactam compounds and pharmaceutical uses thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-07-05 | — | — | EP | disclosed |