Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9803078 | 0.84 | ESR1 (0.34) | ALDH1A1ESR1CYP3A4ESR2CNR1 | |
| SCHEMBL9014936 | 0.83 | PTPN1 (0.54) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL11342008 | 0.82 | PTPN1 (0.53) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL9249295 | 0.81 | PTPN1 (0.58) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL18422328 | 0.80 | CYP3A4 (0.34) | ALDH1A1ESR1CYP3A4ESR2ALOX5AP | |
| SCHEMBL313198 | 0.80 | PTPN1 (0.59) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL7090683 | 0.78 | PTPN1 (0.58) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| Zinc Ion SCHEMBL11341982 | 0.75 | ESR1 (0.42) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 | |
| SCHEMBL7831582 | 0.74 | PTPN1 (0.31) | PTPN1AKR1C2AKR1C1AKR1C3HNF4A | |
| SCHEMBL1129729 | 0.74 | ESR1 (0.46) | PTPN1AKR1C2AKR1C1AKR1C3PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017546-A | Metallized phenolic resins | SCHENECTADY INTERNATIONAL, INC. | 1991-05-21 | — | — | US | disclosed |