SCHEMBL9803374

SCHEMBL9803374

CCCCOc1ccc(-c2ccc(OC(=O)C(Cl)CC(C)C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RARB P10826 5/20 0.48
CYP3A4 P08684 2/20 0.44
CYP2D6 P10635 2/20 0.44
TAS1R3 Q7RTX0 1/20 0.43
TAS1R1 Q7RTX1 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NPC1 O15118 1/20 0.42
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
ACACB O00763 2/20 0.42
PTGES O14684 1/20 0.42
ALOX5 P09917 1/20 0.42
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
ACACA Q13085 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9803621 0.97 RARB (0.52) RARBCYP3A4CYP2D6SMN1; SMN2NPC1
SCHEMBL9803639 0.96 RARB (0.54) RARBCYP3A4CYP2D6SMN1; SMN2NPC1
SCHEMBL9803426 0.96 RARB (0.54) RARBCYP3A4CYP2D6SMN1; SMN2NPC1
SCHEMBL9803372 0.96 RARB (0.54) RARBCYP3A4CYP2D6SMN1; SMN2NPC1
SCHEMBL9803347 0.96 RARB (0.54) RARBCYP3A4CYP2D6SMN1; SMN2NPC1
SCHEMBL9803349 0.96 RARB (0.54) RARBCYP3A4CYP2D6SMN1; SMN2NPC1
SCHEMBL9802921 0.96 RARB (0.54) RARBCYP3A4CYP2D6SMN1; SMN2NPC1
SCHEMBL9803567 0.96 RARB (0.54) RARBCYP3A4CYP2D6SMN1; SMN2NPC1
SCHEMBL9803575 0.96 RARB (0.54) RARBCYP3A4CYP2D6SMN1; SMN2NPC1
SCHEMBL9803458 0.96 RARB (0.54) RARBCYP3A4CYP2D6SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0159872-B1 SMECTIC LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITIONS AJINOMOTO CO., INC. (JP) 1991-03-06 EP disclosed
US-4592858-A HIGH SPEED FERROELECTRIC SWITCHES AJINOMOTO COMPANY, INC. (JP) 1986-06-03 US disclosed
EP-0159872-A2 Smectic liquid crystal compound and liquid crystal compositions AJINOMOTO CO., INC. (JP) 1985-10-30 EP disclosed