Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.58 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.58 |
| ▸ | PPARG | P37231 | 4/20 | 0.56 |
| ▸ | PIM1 | P11309 | 2/20 | 0.55 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1848112 | 0.83 | PPARG (0.61) | HPGDCISD1PPARGPIM1PIM2 | |
| SCHEMBL12521873 | 0.83 | PPARG (0.61) | HPGDCISD1PPARGPIM1PIM2 | |
| SCHEMBL1848111 | 0.83 | PPARG (0.61) | HPGDCISD1PPARGPIM1PIM2 | |
| SCHEMBL1849761 | 0.83 | PPARG (0.66) | HPGDCISD1PPARGPIM1PIM2 | |
| SCHEMBL12521715 | 0.83 | PPARG (0.66) | HPGDCISD1PPARGPIM1PIM2 | |
| SCHEMBL1849759 | 0.83 | PPARG (0.66) | HPGDCISD1PPARGPIM1PIM2 | |
| SCHEMBL1851183 | 0.82 | PPARG (0.61) | HPGDCISD1PPARGPIM1PIM2 | |
| SCHEMBL12521883 | 0.82 | PPARG (0.61) | HPGDCISD1PPARGPIM1PIM2 | |
| SCHEMBL1851182 | 0.82 | PPARG (0.61) | HPGDCISD1PPARGPIM1PIM2 | |
| SCHEMBL1848738 | 0.82 | PPARG (0.68) | HPGDPPARGPIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075300-A | Hypoglycemic and antilipemic agents | BEECHAM GROUP P.L.C. (GB) | 1991-12-24 | — | — | US | claimed |
| US-5075300-A | Hypoglycemic and antilipemic agents | BEECHAM GROUP P.L.C. (GB) | 1991-12-24 | — | — | US | disclosed |