SCHEMBL9804206

SCHEMBL9804206

c1ccc(CC/C(=N/c2ccccc2)Nc2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.54
HTT P42858 1/20 0.54
KMT2A Q03164 3/20 0.49
LMNA P02545 2/20 0.49
GRIN2D O15399 1/20 0.49
GRIN3B O60391 1/20 0.49
CYP2D6 P10635 1/20 0.49
SLC6A2 P23975 1/20 0.49
GRIN1 Q05586 1/20 0.49
GRIN2A Q12879 1/20 0.49
GRIN2B Q13224 1/20 0.49
GRIN2C Q14957 1/20 0.49
GRIN3A Q8TCU5 1/20 0.49
SIGMAR1 Q99720 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
GAA P10253 1/20 0.46
RAB9A P51151 3/20 0.44
NPC1 O15118 2/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9804211 1.00 MAPT (0.54) MAPTHTTKMT2ALMNAGRIN2D
SCHEMBL9804174 0.84 KMT2A (0.53) MAPTKMT2ALMNAGRIN2DGRIN3B
SCHEMBL9804184 0.84 KMT2A (0.53) MAPTKMT2ALMNAGRIN2DGRIN3B
SCHEMBL15246757 0.82 KMT2A (0.52) MAPTHTTKMT2ALMNAGRIN2D
SCHEMBL9804208 0.82 KMT2A (0.52) KMT2ALMNAGRIN2DGRIN3BCYP2D6
SCHEMBL9804138 0.82 KMT2A (0.52) KMT2ALMNAGRIN2DGRIN3BCYP2D6
SCHEMBL9804131 0.82 KMT2A (0.52) KMT2ALMNAGRIN2DGRIN3BCYP2D6
SCHEMBL9804212 0.82 KMT2A (0.52) KMT2ALMNAGRIN2DGRIN3BCYP2D6
SCHEMBL9804147 0.82 KMT2A (0.52) KMT2ALMNAGRIN2DGRIN3BCYP2D6
SCHEMBL9804142 0.82 KMT2A (0.52) KMT2ALMNAGRIN2DGRIN3BCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0153616-B1 HEAT-SENSITIVE RECORDING MATERIALS KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1991-04-03 EP disclosed
US-4652512-A DIAZONIUM COMPOUND KANZAKI PAPER MANUFACTURING COMPANY, LIMITED (JP) 1987-03-24 US disclosed
EP-0153616-A2 Heat-sensitive recording materials KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1985-09-04 EP disclosed