⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941236 | 0.90 | — | — | |
| SCHEMBL9696640 | 0.82 | — | — | |
| SCHEMBL1691304 | 0.80 | — | — | |
| SCHEMBL2011670 | 0.80 | — | — | |
| SCHEMBL2447355 | 0.80 | — | — | |
| SCHEMBL2285843 | 0.78 | — | — | |
| SCHEMBL7016519 | 0.78 | — | — | |
| SCHEMBL4691011 | 0.77 | EPHX1 (0.34) | — | |
| SCHEMBL7691563 | 0.76 | — | — | |
| SCHEMBL14325566 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739070-B2 | C5A receptor modulators | IDORSIA PHARMACEUTICALS LTD. (CH) | 2023-08-29 | — | — | US | disclosed |
| US-20200347029-A1 | C5A RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD. (CH) | 2020-11-05 | — | — | US | disclosed |
| EP-0247485-B1 | PROCESS FOR THE PREPARATION OF OXETAN-3-CARBOXYLIC ACIDS | BAYER AG (DE) | 1991-04-17 | — | — | EP | disclosed |
| EP-0247481-B1 | PROCESS FOR THE PREPARATION OF 2,2-BIS-CHLOROMETHYL-ALKANE-CARBOXYLIC-ACID CHLORIDES | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |
| EP-0247485-A2 | Process for the preparation of oxetan-3-carboxylic acids | BAYER AG (DE) | 1987-12-02 | — | — | EP | disclosed |
| EP-0247481-A1 | Process for the preparation of 2,2-bis-chloromethyl-alkane-carboxylic-acid chlorides | BAYER AG (DE) | 1987-12-02 | — | — | EP | disclosed |