SCHEMBL9804265

SCHEMBL9804265

COC(=O)CCc1cccc(Oc2ccccc2)c1

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 11/20 0.60
FFAR4 Q5NUL3 3/20 0.56
GNA15 P30679 1/20 0.56
PTGER3 P43115 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
PTGES O14684 1/20 0.54
FDFT1 P37268 2/20 0.51
SIRT2 Q8IXJ6 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28575916 0.91 FFAR1 (0.58) FFAR1FFAR4GNA15PTGER3TDP1
SCHEMBL17413720 0.88 FFAR1 (0.60) FFAR1FFAR4
SCHEMBL1744569 0.87 FFAR1 (0.77) FFAR1FFAR4GNA15PTGER3TDP1
SCHEMBL14925270 0.86 FFAR1 (0.80) FFAR1FFAR4GNA15PTGER3TDP1
SCHEMBL1563518 0.86 FFAR1 (0.54) FFAR1FFAR4GNA15PTGER3TDP1
SCHEMBL63100 0.86 HDAC1 (0.61)
SCHEMBL4654749 0.86 FFAR1 (0.70) FFAR1FFAR4TDP1
SCHEMBL9167497 0.85 FFAR1 (0.56) FFAR1FFAR4GNA15PTGER3TDP1
SCHEMBL10683288 0.85 FFAR1 (0.63) FFAR1FFAR4PTGES
SCHEMBL5047991 0.85 KDM4E (0.62) FFAR1FFAR4GNA15PTGER3TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114269974-A Sheath-core filaments comprising crosslinkable and crosslinked binder compositions and methods of printing 3M创新有限公司 2022-04-01 CN disclosed
EP-0240121-B1 DIPHENYL ETHER DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-04-17 EP disclosed
EP-0390228-A2 Chemical intermediates IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-10-03 EP disclosed
US-4791139-A Diphenyl ether derivatives and their use as insecticides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-12-13 US disclosed
CN-87102455-A Diphenyl ether derivatives pesticide compound 1988-01-27 CN disclosed
EP-0240121-A2 Diphenyl ether derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-10-07 EP disclosed