Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CETP | P11597 | 2/20 | 0.47 |
| ▸ | FDFT1 | P37268 | 12/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7930475 | 0.91 | FDFT1 (0.52) | CETPFDFT1 | |
| SCHEMBL9804588 | 0.90 | FDFT1 (0.45) | KDM4EALDH1A1HTTSMN1; SMN2CETP | |
| SCHEMBL9804456 | 0.89 | FDFT1 (0.54) | CETPFDFT1 | |
| SCHEMBL9804670 | 0.88 | FDFT1 (0.56) | CETPFDFT1 | |
| SCHEMBL7931627 | 0.88 | CETP (0.49) | CETPFDFT1LTA4H | |
| SCHEMBL7931643 | 0.88 | FDFT1 (0.47) | CETPFDFT1 | |
| SCHEMBL7934874 | 0.88 | FDFT1 (0.53) | ALDH1A1CETPFDFT1 | |
| SCHEMBL9804343 | 0.88 | FDFT1 (0.58) | CETPFDFT1LTA4H | |
| SCHEMBL9804516 | 0.88 | FDFT1 (0.53) | CETPFDFT1LTA4H | |
| SCHEMBL9492405 | 0.88 | CETP (0.50) | CETPFDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| EP-0390228-A2 | Chemical intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-03 | — | — | EP | disclosed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |
| CN-87102455-A | Diphenyl ether derivatives pesticide compound | — | 1988-01-27 | — | — | CN | disclosed |
| EP-0240121-A2 | Diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-07 | — | — | EP | disclosed |