Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CASR | P41180 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GRK3 | P35626 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61312 | 0.92 | KDM4E (0.42) | KDM4ECASRUSP2ALDH1A1KMT2A | |
| SCHEMBL62207 | 0.91 | KDM4E (0.41) | KDM4ECASRUSP2ALDH1A1KMT2A | |
| SCHEMBL15218970 | 0.91 | KDM4E (0.41) | KDM4ECASRUSP2ALDH1A1KMT2A | |
| SCHEMBL15218997 | 0.90 | KDM4E (0.40) | KDM4ECASRUSP2ALDH1A1KMT2A | |
| SCHEMBL28020280 | 0.88 | KDM4E (0.42) | KDM4ECASRUSP2ALDH1A1KMT2A | |
| SCHEMBL19697517 | 0.88 | POLB (0.42) | KDM4ECASRALDH1A1KMT2AADRB2 | |
| SCHEMBL9927969 | 0.88 | KDM4E (0.39) | KDM4ECASRUSP2ALDH1A1KMT2A | |
| SCHEMBL18102291 | 0.88 | KDM4E (0.39) | KDM4ECASRUSP2ALDH1A1KMT2A | |
| SCHEMBL15218990 | 0.86 | KDM4E (0.37) | KDM4ECASRUSP2ALDH1A1KMT2A | |
| SCHEMBL14865748 | 0.85 | KDM4E (0.36) | KDM4ECASRALDH1A1KMT2AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276138-B1 | CHROMATOGRAPHIC SUPPORTS FOR SEPARATION OF OLIGONUCLEOTIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-17 | — | — | EP | disclosed |
| US-4767670-A | PACKING INCLUDES POROUS SUPPORT WITH SILAND BONDED TO ANION EXCHANGE GROUP | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-08-30 | — | — | US | disclosed |